Chemical constituents and leishmanicidal activity from leaves of Kielmeyera variabilis
نویسندگان
چکیده
منابع مشابه
Antibacterial xanthones from Kielmeyera variabilis mart. (Clusiaceae).
The bioassay-guided fractionation of stems from Kielmeyera variabilis, traditionally used in Brazilian folk medicine, yielded assiguxanthone-B (1), kielcorin (4), 2,5-dihydroxybenzoic acid (3), and a mixture of xanthones containing assiguxanthone-B (1) and 1,3,5,6-tetrahydroxy-2-prenylxanthone (2) (1:1 w/w). The xanthone mixture inhibited Staphylococcus aureus and Bacillus subtilis at a concent...
متن کاملFree radical scavenging activity of Kielmeyera variabilis (Clusiaceae).
As part of our ongoing research on antioxidant agents from Brazilian flora, we screened the free radical scavenging activity of two extracts and eight fractions of Kielmeyera variabilis (Clusiaceae) using DPPH· (2,2-diphenyl-1-picrylhydrazyl-hydrate) and ABTS·+ [2,2'-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] colorimetric assays. The ethyl acetate and n-butanol fractions of the leaves...
متن کاملChemical Constituents Isolated from Leaves of Barleria
Two phenolic compounds (PCoumaric acid and α–Tocopherol), two flavonoidal compounds ( luetoline and 7-methoxy luetoline) and two iridoidal glycosides (barlerin and schanshiside methyl ester) have been isolated from leaves of Barleria cristata their structure were established by spectral analysis. This is the first report of occurrence of these compounds from Barleria cristata Linn plant. K. HEM...
متن کاملLeishmanicidal Activity and Structure-Activity Relationships of Essential Oil Constituents.
Several constituents of essential oils have been shown to be active against pathogens such as bacteria, fungi, and protozoa. This study demonstrated the in vitro action of ten compounds present in essential oils against Leishmania amazonensis promastigotes. With the exception of p-cymene, all evaluated compounds presented leishmanicidal activity, exhibiting IC50 between 25.4 and 568.1 μg mL-1. ...
متن کاملChemical composition and leishmanicidal activity of Pulicaria gnaphalodes essential oil
Background and objectives: Several natural compounds have been identified for the treatment ofleishmaniasis. Due to a few safe drugs and the side effects caused by available chemotherapy, some new drugs for treatment of leishmaniasis are requested. The genus Pulicaria (Asteraceae) is represented in the flora of Iran by five species. Phytochemical studies on Pulicaria...
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ژورنال
عنوان ژورنال: Revista Brasileira de Farmacognosia
سال: 2012
ISSN: 0102-695X
DOI: 10.1590/s0102-695x2012005000095